产品货号：
Z27292
中文名称：
SWAP70抗体
英文名称：
Anti-SWAP70 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SWAP70 Antibody |
| 指标别名 | SWAP70;KIAA0640;HSPC321;Switch-associated protein 70;SWAP-70 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | SWAP70 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SWAP70 recombinant protein (Position:H161-K292). |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SWAP70 (Switch-associated protein 70) is a 67～70kDa intracellular protein that bears limited resemblance to members of the Dbl-family of GEFs for small Rho GTPases.It is expressed in mast cells,dendritic cells and B cells.In mast cells,it promotes the release of anaphylactic mediators;in dendritic cells,it regulates the appearance of MHC II;and in B cells,it forms a nuclear complex that initiates immunoglobulin class switching.Human SWAP70 is 585 amino acids (aa) in length.It contains one plextrin homology (PH) domain (aa 213-304) plus a coiled-coil region (aa 316-539).There are three potential splice variants.One contains an alternative start site at Met70,another shows a deletion of aa 81-138,and a third possesses a 38 aa substitution for aa 453-585.Over aa 386-585,human SWAP70 shares 96% aa identity with mouse SWAP70. |
| Uniprot ID | Q9UH65 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | switching B cell complex subunit SWAP70 |
| 蛋白名全称 | Switch-associated protein 70 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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